This one is quite straight forward. Is the performance of the application when delivered with App-V sufficient? If it’s not you may prefer to deliver the application locally or alternatively via RDS or XenApp, though both of those
This was a tough one to put a label on. Here I’m referring to commonly shared dependencies. This could be Java, Flash Player, VB runtimes, Access runtimes or other forms of runtime, middleware or even just a widely required pre-requisite\dependency.