As we all know, sequencing Internet Explorer is not supported but you can sequence IE plugins and other settings required by web apps and simply create a shortcut pointing to the locally installed Internet Explorer.
Studio interprets the shortcut correctly. However, in earlier versions of 7.x, there’s an issue on the VDA with launching apps using the /appvve parameter. The end result you may see is that IE launches but puts your appvve argument into the URL and not launch within the App-V app.
This may come as bad news but you will need 7.6 CU3 or later if you are LTSR or 7.8 or later.